The J-Lite JLA-16.250 fixed angle rotor is a lightweight alternative to conventional 250 mL rotors and is suitable for general purpose, large-volume, and multitube processing applications.Rated for 16,000 RPM in Beckman Coulter Avanti J series centrifuges and 14,000 RPM in Beckman Coulter J2 series centrifuges, the JLA-16.250 rotor is designed to hold up to six 250-mL bottles at a 25-degree angle to the axis of rotation, and develops centrifugal forces that can efficiently pellet cells from large volumes, or cell particles from tissue homogenates. Short column methods (such as partially filled tubes) may also be used to purify large quantities of virus in a cushion gradient.An available dual-locking lid mechanism allows the rotor to be loaded into and removed from the centrifuge with the lid in place. The rotor may be placed under a safety hood before the lid is attached or removed. If biosafety is not a concern, a single-locking lid mechanism is also available.