RNA and cDNA Cleanup

RNAClean XP

Purify RNA and cDNA from common enzymatic reactions using our proprietary SPRI paramagnetic bead-based chemistry.

  • Compatible with manual and automated processing
  • Complete removal of salts, unincorporated primers and dNTPs
  • Used in RNA-Seq library preparations
  • Certified RNAse-free

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Explore RNAClean XP Reagents

Explore RNAClean XP Reagents

RNAClean XP Workflow Steps

Genomics RNAClean XP Workflow

Product Features

Overview

RNAClean XP purifies cDNA and RNA from common enzymatic reactions.

High Recovery

Efficient recovery of your sample ensures that critical data is not lost within the workflow.

Flexible

Manual, hands-on cleanups using RNAClean XP require less than 30 minutes.

Scalable

For higher throughput needs, RNAClean XP is automated on Biomek platforms enabling hundreds of samples per day.

Citations

Donega, V., Burm, S. M., van Strien, M. E., van Bodegraven, E. J., Paliukhovich, I., Geut, H., . . . Hol, E. M. (2019). Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson’s disease. Acta Neuropathologica Communications, 7(4). doi:10.1186/s40478-019-0736-0

  • Used to clean up amplified RNA

Warner, A. D., Gevirtzman, L., Hillier, L. W., Ewing, B., & Waterston, R. H. (2019, May 23). The C. elegans embryonic transcriptome with tissue, time, and alternative splicing resolution. Genome Research. doi:10.1101/gr.243394.118

  • Used to clean up RNA post rRNA removal

Caro-Vegas, C., Bailey, A., Bigi, R., Bamania, B., & Dittmer, D. P. (2019, January/February). Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma. mBio, 10(1), e02871-18. doi:10.1128/mBio.02871-18

  • Used to clean up fragmented RNA and cDNA 

Disclaimer: Beckman Coulter makes no warranties of any kind whatsoever express or implied, with respect to this protocol, including but not limited to warranties of fitness for a particular purpose or merchantability or that the protocol is non-infringing. All warranties are expressly disclaimed. Your use of the method is solely at your own risk, without recourse to Beckman Coulter. Not intended or validated for use in the diagnosis of disease or other conditions. This protocol is for demonstration only, and is not validated by Beckman Coulter.

Content and Resources

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Technical Documents

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